Mortality in people with intellectual disabilities and epilepsy : a systematic review

Robertson, Janet and Hatton, Chris and Emerson, Eric and Baines, Susannah (2015) Mortality in people with intellectual disabilities and epilepsy : a systematic review. Seizure - European Journal of Epilepsy, 29. pp. 123-133. ISSN 1059-1311

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Purpose: Epilepsy is highly prevalent in people with intellectual disabilities and mortality is increased in people with epilepsy generally. This review summarises research on the comparative risk of mortality in people with intellectual disabilities and epilepsy compared to the general population, people with intellectual disabilities without epilepsy, and people with epilepsy without intellectual disabilities. Method: Studies were identified via electronic searches using Medline, Cinahl and PsycINFO and cross-citations. Information extracted from studies was tabulated and reviewed narratively. Results: Sixteen studies met the inclusion criteria. Epilepsy was associated with increased mortality in people with intellectual disabilities in most studies, particularly in those experiencing recent seizures. Further research is needed to substantiate some of the reported findings. Conclusion: Services must be equipped with the skills and information needed to manage this condition in order to minimise the risk of death in people with intellectual disabilities and epilepsy. (C) 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Item Type:
Journal Article
Journal or Publication Title:
Seizure - European Journal of Epilepsy
Additional Information:
This is the author’s version of a work that was accepted for publication in Seizure. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Seizure, 29, 2015 DOI: 10.1016/j.seizure.2015.04.004
Uncontrolled Keywords:
?? epilepsymortalityintellectual disabilitiessudden unexpected deathremote symptomatic epilepsymental-retardationcancer incidencedown-syndromerisk-factorsepidemiologyprevalencechildrencohortclinical neurologyneurology ??
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Deposited On:
17 Nov 2015 09:30
Last Modified:
28 Nov 2023 11:22