Electrical stimulation of human mesenchymal stem cells on biomineralized conducting polymers enhances their differentiation towards osteogenic outcomes

Hardy, John G. and Sukhavasi, Rushi C. and Aguilar Jr., David and Villancio-Wolter, Maria and Mouser, David J. and Geissler, Sydney and Nguy, Lindsey and Chow, Jacqueline K. and Kaplan, David L. and Schmidt, Christine E. (2015) Electrical stimulation of human mesenchymal stem cells on biomineralized conducting polymers enhances their differentiation towards osteogenic outcomes. Journal of Materials Chemistry B, 3 (41). pp. 8059-8064. ISSN 2050-750X

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Abstract

Tissue scaffolds allowing the behaviour of the cells that reside on them to be controlled are of particular interest for tissue engineering. Herein we describe biomineralized conducting polymer-based bone tissue scaffolds that facilitate the electrical stimulation of human mesenchymal stem cells, resulting in enhancement of their differentiation towards osteogenic outcomes.