Electrical stimulation of human mesenchymal stem cells on conductive nanofibers enhances their differentiation toward osteogenic outcomes

Hardy, John and Villancio-Wolter, Maria and Sukhavasi, Rushi and Mouser, David and Aguilar, David and Geissler, Sydney and Kaplan, David and Schmidt, Christine (2015) Electrical stimulation of human mesenchymal stem cells on conductive nanofibers enhances their differentiation toward osteogenic outcomes. Macromolecular Rapid Communications, 36 (21). pp. 1884-1890. ISSN 1022-1336

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Abstract

Tissue scaffolds allowing the behaviour of the cells that reside within them to be controlled are of particular interest for tissue engineering. Herein we describe the preparation of conductive fiber-based bone tissue scaffolds (nonwoven mats of electrospun polycaprolactone with an interpenetrating network of polypyrrole and polystyrenesulfonate) that enable the electrical stimulation of human mesenchymal stem cells to enhance their differentiation towards osteogenic outcomes.

Item Type:
Journal Article
Journal or Publication Title:
Macromolecular Rapid Communications
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1500/1501
Subjects:
?? conducting polymerselectrical stimulationtissue scaffoldstem cellsbonebioengineeringelectrochemistrybiomaterialschemical engineering (miscellaneous)biomaterialsmaterials chemistryorganic chemistrypolymers and plasticssdg 3 - good health and well-being ??
ID Code:
75394
Deposited By:
Deposited On:
21 Oct 2015 04:58
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 15:23