Hardy, John G. and Geissler, Sydney A. and Aguilar Jr., David and Villancio-Wolter, Maria K. and Mouser, David J. and Sukhavasi, Rushi C. and Cornelison, R. Chase and Tien, Lee W. and Preda, R. Carmen and Hayden, Rebecca S. and Chow, Jacqueline K. and Nguy, Lindsey and Kaplan, David L. and Schmidt, Christine E. (2015) Instructive conductive 3D silk foam-based bone tissue scaffolds enable electrical stimulation of stem cells for enhanced osteogenic differentiation. Macromolecular Bioscience, 15 (11). pp. 1490-1496. ISSN 1616-5187
Hardy_Kaplan_Schmidt_MBS_SI_pure.pdf - Accepted Version
Available under License Creative Commons Attribution-NonCommercial.
Download (469kB)
Hardy_Kaplan_Schmidt_MBS_Manuscript_Pure.pdf - Accepted Version
Available under License Creative Commons Attribution-NonCommercial.
Download (659kB)
Abstract
Stimuli-responsive materials enabling the behaviour of the cells that reside within them to be controlled are vital for the development of instructive tissue scaffolds for tissue engineering. Herein we describe the preparation of conductive silk foam-based bone tissue scaffolds that enable the electrical stimulation of human mesenchymal stem cells to enhance their differentiation towards osteogenic outcomes.