Hardy, John G. and Pfaff, Andre and Leal-Egana, Aldo and Mueller, Axel H. E. and Scheibel, Thomas R. (2014) Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion. Macromolecular Bioscience, 14 (7). pp. 936-942. ISSN 1616-5187
Full text not available from this repository.Abstract
Silk protein-based materials are promising biomaterials for application as tissue scaffolds, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) and their functionalization with glycopolymers are described. The glycopolymers bind proteins found in the extracellular matrix, providing a biomimetic coating on the films that improves cell adhesion to the surfaces of engineered spider silk films. Such silk-based materials have potential as coatings for degradable implantable devices.