Regioswitchable palladium-catalyzed decarboxylative coupling of 1,3-dicarbonyl compounds

Kenny, Miles and Christensen, Jeppe and Coles, Simon and Franckevicius, Vilius (2015) Regioswitchable palladium-catalyzed decarboxylative coupling of 1,3-dicarbonyl compounds. Organic Letters, 17 (15). pp. 3926-3929. ISSN 1523-7060

[thumbnail of Franckevicius Manuscript REVISED FINAL]

Preview

PDF (Franckevicius Manuscript REVISED FINAL)
Franckevicius_Manuscript_REVISED_FINAL.pdf - Accepted Version
Available under License Creative Commons Attribution.
Download (626kB)

Abstract

A palladium-catalyzed chemo- and regioselective coupling of 1,3-dicarbonyl compounds via an allylic linker has been developed. This reaction, which displays broad substrate scope, forms two C−C bonds and installs two all-carbon quaternary centers. The regioselectivity of the reaction can be predictably controlled by utilizing an enol carbonate of one of the coupling partners.

Item Type:

Journal Article

Journal or Publication Title:

Organic Letters

Additional Information:

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://pubs.acs.org/doi/abs/10.1021/acs.orglett.5b01979

Uncontrolled Keywords:

/dk/atira/pure/subjectarea/asjc/1300/1303

Subjects:

?? biochemistryorganic chemistryphysical and theoretical chemistry ??

ID Code:

75369

Deposited By:

ep_importer_pure

Deposited On:

09 Sep 2015 06:32

Refereed?:

Yes

Published?:

Published

Last Modified:

21 Oct 2024 23:44

URI:

https://eprints.lancs.ac.uk/id/eprint/75369