Regioswitchable palladium-catalyzed decarboxylative coupling of 1,3-dicarbonyl compounds

Kenny, Miles and Christensen, Jeppe and Coles, Simon and Franckevicius, Vilius (2015) Regioswitchable palladium-catalyzed decarboxylative coupling of 1,3-dicarbonyl compounds. Organic Letters, 17 (15). pp. 3926-3929. ISSN 1523-7060

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Abstract

A palladium-catalyzed chemo- and regioselective coupling of 1,3-dicarbonyl compounds via an allylic linker has been developed. This reaction, which displays broad substrate scope, forms two C−C bonds and installs two all-carbon quaternary centers. The regioselectivity of the reaction can be predictably controlled by utilizing an enol carbonate of one of the coupling partners.

Item Type:
Journal Article
Journal or Publication Title:
Organic Letters
Additional Information:
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://pubs.acs.org/doi/abs/10.1021/acs.orglett.5b01979
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1600/1606
Subjects:
ID Code:
75369
Deposited By:
Deposited On:
09 Sep 2015 06:32
Refereed?:
Yes
Published?:
Published
Last Modified:
11 Jul 2020 05:21