Regioswitchable palladium-catalyzed decarboxylative coupling of 1,3-dicarbonyl compounds

Kenny, Miles and Christensen, Jeppe and Coles, Simon and Franckevicius, Vilius (2015) Regioswitchable palladium-catalyzed decarboxylative coupling of 1,3-dicarbonyl compounds. Organic Letters, 17 (15). pp. 3926-3929. ISSN 1523-7060

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A palladium-catalyzed chemo- and regioselective coupling of 1,3-dicarbonyl compounds via an allylic linker has been developed. This reaction, which displays broad substrate scope, forms two C−C bonds and installs two all-carbon quaternary centers. The regioselectivity of the reaction can be predictably controlled by utilizing an enol carbonate of one of the coupling partners.

Item Type:
Journal Article
Journal or Publication Title:
Organic Letters
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This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see
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?? biochemistryorganic chemistryphysical and theoretical chemistry ??
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Deposited On:
09 Sep 2015 06:32
Last Modified:
05 Feb 2024 00:36