Patient-reported outcome measures for use in gynaecological oncology : a systematic review

Preston, Nancy J. and Wilson, Nadine and Wood, N. J. and Brine, Jenny and Ferreira Arcuri, Juliano and Brearley, Sarah G. (2015) Patient-reported outcome measures for use in gynaecological oncology : a systematic review. BJOG: An International Journal of Obstetrics and Gynaecology, 122 (5). pp. 615-622. ISSN 1470-0328

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Background Patient-reported outcome measures (PROMs) are used to assess the impact of health care on a patient's health. Within the gynaecological oncology setting, multiple PROMs have been adopted but no assessment has been made in terms of their psychometric qualities and robustness. Objectives To undertake a systematic review to identify the most psychometrically robust and appropriate PROM used in the gynaecological oncology setting. Search strategy A search of the bibliographic database of the Oxford PROM group, plus nine additional databases, was carried out along with citation-tracking and hand searches. Selection criteria Studies examining the psychometric properties of outcome measures tested in gynaecological cancer populations were selected by three blinded reviewers. Data collection and analysis Studies were independently assessed and data extracted. Analysis included an appraisal of the psychometric properties and functionality of the included PROMs to guide recommendations. Main results Eighteen PROMs tested in gynaecological oncology settings were identified. These were categorised into seven areas of focus, and the most psychometrically robust tools were identified: (1) generic (no recommendation); (2) general cancer (EORTC QLQ-C30 and FACT-G); (3) pelvic cancer (QUESTGY); (4) ovarian cancer (EORTC QLQ-OV28); (5) cervical cancer (EORTC QLQ-CX24); (6) endometrial cancer (EORTC QLQ-EN 24); and (7) vulval cancer (FACT-V). Author's conclusions Seven PROMs were recommended for use in six gynaecological populations. No single tool was identified that had been tested in all disease groups. Some showed promise, but a lack of conceptual clarity about the core outcomes and the rationale for use will require further testing using well-constructed studies.

Item Type:
Journal Article
Journal or Publication Title:
BJOG: An International Journal of Obstetrics and Gynaecology
Uncontrolled Keywords:
?? cancergynaecological oncologymetricsoutcomespatient-reported outcome measurespsychometric propertiesquality-of-lifecervical-cancerovarian-cancerclinical-practicepsychometric propertieseuropean organizationfunctional assessmentchinese versioneortc qlq-cx24 ??
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Deposited On:
08 Jul 2015 08:40
Last Modified:
28 Nov 2023 11:21