Mitochondrial replacement : ethics and identity

Wrigley, Anthony and Wilkinson, Stephen and Appleby, John (2015) Mitochondrial replacement : ethics and identity. Bioethics, 29 (9). pp. 631-638. ISSN 0269-9702

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Mitochondrial replacement techniques (MRTs) have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer (PNT) and Maternal Spindle Transfer (MST). It examines how questions of identity impact on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST.

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© 2015 The Authors. Bioethics published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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?? philosophyhealth(social science)health policy ??
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22 Jun 2015 15:16
Last Modified:
18 Dec 2023 01:29