Gold nanoparticles as a substrate in bio-analytical near-infrared surface-enhanced Raman spectroscopy

Butler, Holly J. and Fogarty, Simon W. and Kerns, Jemma G. and Martin-Hirsch, Pierre L. and Fullwood, Nigel J. and Martin, Francis L. (2015) Gold nanoparticles as a substrate in bio-analytical near-infrared surface-enhanced Raman spectroscopy. Analyst, 140 (9). pp. 3090-3097. ISSN 0003-2654

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Abstract

As biospectroscopy techniques continue to be developed for screening or diagnosis within a point-ofcare setting, an important development for this field will be high-throughput optimization. For many of these techniques, it is therefore necessary to adapt and develop parameters to generate a robust yet simple approach delivering high-quality spectra from biological samples. Specifically, this is important for surface-enhanced Raman spectroscopy (SERS) wherein there are multiple variables that can be optimised to achieve an enhancement of the Raman signal from a sample. One hypothesis is that "large" diameter (>100 nm) gold nanoparticles provide a greater enhancement at near-infrared (NIR) and infrared (IR) wavelengths than those

Item Type:
Journal Article
Journal or Publication Title:
Analyst
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1600/1603
Subjects:
ID Code:
74090
Deposited By:
Deposited On:
18 Jun 2015 06:01
Refereed?:
Yes
Published?:
Published
Last Modified:
03 Jun 2020 02:48