Simon’s minimax and optimal and Jung’s admissible two-stage design with or without curtailment

Kunz, Cornelia and Kieser, Meinhard (2011) Simon’s minimax and optimal and Jung’s admissible two-stage design with or without curtailment. Stata Journal, 11 (2). pp. 240-254. ISSN 1536-867X

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Abstract

This article describes a new Stata command called simontwostage, which calculates the critical values and sample sizes for two-stage designs for phase II oncology trials. Options are provided to determine the minimax and optimal designs proposed by Simon (1989, Controlled Clinical Trials 10: 1–10) and admissible designs described by Jung et al. (2004, Statistics in Medicine 23: 561–569). Furthermore, nonstochastic and stochastic curtailment rules can be implemented in both stages of the trial, and the properties of the curtailed designs can be examined.

Item Type:
Journal Article
Journal or Publication Title:
Stata Journal
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2600/2601
Subjects:
ID Code:
73939
Deposited By:
Deposited On:
18 Jun 2015 05:57
Refereed?:
Yes
Published?:
Published
Last Modified:
07 Jan 2020 04:12