Superficial amygdala and hippocampal activity during affective music listening observed at 3 T but not 1.5 T fMRI

Skouras, Stavros and Gray, Marcus and Critchley, Hugo and Koelsch, Stefan (2014) Superficial amygdala and hippocampal activity during affective music listening observed at 3 T but not 1.5 T fMRI. NeuroImage, 101. pp. 364-369. ISSN 1053-8119

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Abstract

The purpose of this study was to compare 3 T and 1.5 T fMRI results during emotional music listening. Stimuli comprised of psychoacoustically balanced instrumental musical pieces, with three different affective expressions (fear, neutral, joy). Participants (N=32) were split into two groups, one subjected to fMRI scanning using 3 T and another group scanned using 1.5 T. Whole brain t-tests (corrected for multiple comparisons) compared joy and fear in each of the two groups. The 3 T group showed significant activity differences between joy and fear localized in bilateral superficial amygdala, bilateral hippocampus and bilateral auditory cortex. The 1.5 T group showed significant activity differences between joy and fear localized in bilateral auditory cortex and cuneus. This is the first study to compare results obtained under different field strengths with regard to affective processes elicited by means of auditory/musical stimulation. The findings raise concern over false negatives in the superficial amygdala and hippocampus in affective studies conducted under 1.5 T and caution that imaging improvements due to increasing magnetic field strength can be influenced by region-specific characteristics.

Item Type:
Journal Article
Journal or Publication Title:
NeuroImage
Additional Information:
Copyright © 2014. Published by Elsevier Inc.
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2800/2808
Subjects:
ID Code:
73821
Deposited By:
Deposited On:
18 Jun 2015 05:45
Refereed?:
Yes
Published?:
Published
Last Modified:
26 May 2020 04:04