Recovery-focused cognitive-behavioural therapy for recent-onset bipolar disorder:randomised controlled pilot trial

Jones, Steven H. and Smith, Gina and Mulligan, Lee D. and Lobban, Fiona and Law, Heather and Dunn, Graham and Welford, Mary and Kelly, James and Mulligan, John and Morrison, Anthony P. (2015) Recovery-focused cognitive-behavioural therapy for recent-onset bipolar disorder:randomised controlled pilot trial. British Journal of Psychiatry, 206 (1). pp. 58-66. ISSN 0007-1250

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Abstract

Background Despite evidence for the effectiveness of structured psychological therapies for bipolar disorder no psychological interventions have been specifically designed to enhance personal recovery for individuals with recent-onset bipolar disorder. Aims A pilot study to assess the feasibility and effectiveness of a new intervention, recovery-focused cognitive-behavioural therapy (CBT), designed in collaboration with individuals with recent-onset bipolar disorder intended to improve clinical and personal recovery outcomes. Method A single, blind randomised controlled trial compared treatment as usual (TAU) with recovery-focused CBT plus TAU (n = 67). Results Recruitment and follow-up rates within 10% of pre-planned targets to 12-month follow-up were achieved. An average of 14.15 h (s.d. = 4.21) of recovery-focused CBT were attended out of a potential maximum of 18 h. Compared with TAU, recovery-focused CBT significantly improved personal recovery up to 12-month follow-up (Bipolar Recovery Questionnaire mean score 310.87, 95% CI 75.00-546.74 (s.e. = 120.34), P = 0.010, d = 0.62) and increased time to any mood relapse during up to 15 months follow-up (χ(2) = 7.64, P<0.006, estimated hazard ratio (HR) = 0.38, 95% CI 0.18-0.78). Groups did not differ with respect to medication adherence. Conclusions Recovery-focused CBT seems promising with respect to feasibility and potential clinical effectiveness. Clinical- and cost-effectiveness now need to be reliably estimated in a definitive trial.

Item Type:
Journal Article
Journal or Publication Title:
British Journal of Psychiatry
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2700/2738
Subjects:
ID Code:
72624
Deposited By:
Deposited On:
27 Jan 2015 08:22
Refereed?:
Yes
Published?:
Published
Last Modified:
16 Jul 2020 03:52