Generation and characterization of the pyranosyl and furanosyl oxocarbenium ions from 2-deoxyaldoses

Akien, Geoffrey and Subramaniam, Bala (2014) Generation and characterization of the pyranosyl and furanosyl oxocarbenium ions from 2-deoxyaldoses. In: 247th ACS National Meeting, 2014-03-16 - 2014-03-21, Texas.

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Abstract

Previously, we were able to generate and spectroscopically characterize the (tertiary) oxocarbenium ions from various protected ketofuranoses and ketopyranoses, in superacidic solutions at low temperature. For such complex species, it was perhaps surprising that they were stable at all in superacidic media. We have now extended this methodology to the even more reactive secondary oxocarbenium ions obtainable from various protected 2-deoxyaldoses. Through the measurement of J-couplings, this has allowed for the first determination of the conformation of these important intermediates in solution.

Item Type:
Contribution to Conference (Other)
Journal or Publication Title:
247th ACS National Meeting
ID Code:
72459
Deposited By:
Deposited On:
22 Jan 2015 10:17
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 08:25