Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives

Filby, Maria H. and Muldoon, James and Dabb, Serin and Fletcher, Nicholas C. and Ashcroft, Alison E. and Wilson, Andrew J. (2011) Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives. Chemical Communications, 47 (1). pp. 559-561. ISSN 1359-7345

Abstract

This manuscript illustrates that the geometric arrangement of protein-binding groups around a ruthenium(II) core leads to dramatic differences in cytochrome c (cyt c) binding highlighting that it is possible to define synthetic receptors with shape complementarity to protein surfaces.