Expedient approach to chiral cyclobutanones:asymmetric synthesis of cyclobut-G

Darses, Benjamin and Greene, Andrew E. and Coote, Susannah C. and Poisson, Jean-Francois (2008) Expedient approach to chiral cyclobutanones:asymmetric synthesis of cyclobut-G. Organic Letters, 10 (5). pp. 821-824. ISSN 1523-7060

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Abstract

An efficient one-pot asymmetric synthesis of cyclobutanones from chiral enol ethers is described. The approach is illustrated with alkyl- and functionalized alkyl-substituted enol ethers (nine examples). A new enantioselective synthesis of cyclobut-G (Lobucavir) could thus be achieved.

Item Type:
Journal Article
Journal or Publication Title:
Organic Letters
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1600/1606
Subjects:
ID Code:
72301
Deposited By:
Deposited On:
05 Jan 2015 11:24
Refereed?:
Yes
Published?:
Published
Last Modified:
01 Jan 2020 09:05