Age-associated changes of brain copper, iron, and zinc in Alzheimer's disease and dementia with Lewy bodies

Graham, Stewart F. and Nasaruddin, Muhammad Bin and Carey, Manus and Holscher, Christian and McGuinness, Bernadette and Kehoe, Patrick G. and Love, Seth and Passmore, Peter and Elliott, Christopher T. and Meharg, Andrew A. and Green, Brian D. (2014) Age-associated changes of brain copper, iron, and zinc in Alzheimer's disease and dementia with Lewy bodies. Journal of Alzheimer's Disease, 42 (4). pp. 1407-1413. ISSN 1387-2877

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Abstract

Disease-, age-, and gender-associated changes in brain copper, iron, and zinc were assessed in postmortem neocortical tissue (Brodmann area 7) from patients with moderate Alzheimer's disease (AD) (n = 14), severe AD (n = 28), dementia with Lewy bodies (n = 15), and normal age-matched control subjects (n = 26). Copper was lower (20%; p

Item Type:
Journal Article
Journal or Publication Title:
Journal of Alzheimer's Disease
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2700/2738
Subjects:
ID Code:
70029
Deposited By:
Deposited On:
18 Jul 2014 07:58
Refereed?:
Yes
Published?:
Published
Last Modified:
19 Feb 2020 08:18