Oral corticosteroids for bronchiectasis (stable and acute exacerbations)

Lasserson, Toby J. and Holt, Kay and Milan, Stephen and Greenstone, Michael (2001) Oral corticosteroids for bronchiectasis (stable and acute exacerbations). Cochrane Database of Systematic Reviews. ISSN 1469-493X

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Abstract Background Inflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasis Objectives To determine the efficacy of oral corticosteroids in acute and stable bronchiectasis Search methods The Cochrane Airways Group Specialised Register was searched and bibliographies of retrieved papers were checked. Searches are current as of May 2011. Selection criteria Only randomised controlled trials were considered Data collection and analysis No trials met the inclusion criteria for the review. Main results No randomised controlled trials were identified Authors' conclusions There are no randomised trials upon which to base recommendations about the use of oral corticosteroids in acute or stable bronchiectasis. Plain language summary Oral corticosteroids for bronchiectasis (stable and acute exacerbations) Bronchiectasis is a chronic respiratory disease. People with the condition experience difficulty in clearing mucus from their lungs, leaving them prone to infections. Oral steroids have a place in the management of acute and severe asthma. In bronchiectasis, inhaled steroids have small benefits but there is no evidence for or against the use of oral steroids for this condition.

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Journal Article
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Cochrane Database of Systematic Reviews
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18 Jun 2014 08:36
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18 Sep 2023 00:48