Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

Porter, D. W. and Kerr, B. D. and Flatt, P. R. and Hölscher, Christian and Gault, V. A. (2010) Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance. Diabetes, Obesity and Metabolism, 12 (10). pp. 891-899. ISSN 1463-1326

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Abstract

Liraglutide is a long-acting glucagon-like peptide-1 (GLP-1) mimetic which is a treatment option for type 2 diabetes. GLP-1 peptides, including Liraglutide, cross the blood-brain barrier and may additionally act to improve brain function. The present study tested the hypothesis that, in addition to its antihyperglycaemic actions, peripheral administration of Liraglutide exerts positive actions on cognitive function in mice with high fat dietary-induced obesity and insulin resistance.

Item Type:
Journal Article
Journal or Publication Title:
Diabetes, Obesity and Metabolism
Additional Information:
© 2010 Blackwell Publishing Ltd.
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1300/1310
Subjects:
ID Code:
69066
Deposited By:
Deposited On:
04 Apr 2014 10:15
Refereed?:
Yes
Published?:
Published
Last Modified:
24 Nov 2020 02:49