Small regions of preferential codon usage and their effect on overall codon bias:the case of the plp gene

Gatherer, Derek and McEwan, Neil R. (1997) Small regions of preferential codon usage and their effect on overall codon bias:the case of the plp gene. Biochemistry and Molecular Biology International, 43 (1). pp. 107-114. ISSN 1039-9712

Full text not available from this repository.

Abstract

Preferential codon usage within synonymous groups (codon bias), is hypothesised to be a consequence of either mutational pressure or translational selection. This paper examines PLP and DM-20, two transcripts differentially spliced from the pip gene, using a variety of previously described indices measuring codon bias as well as a novel index for quantifying the response to directional mutation pressure. The results demonstrate that small regions of extreme codon bias may have appreciable effects on the quantification of total bias, and that this effect may be either an increase or a decrease depending which index is used.

Item Type: Journal Article
Journal or Publication Title: Biochemistry and Molecular Biology International
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/1300/1312
Subjects:
Departments: Faculty of Health and Medicine > Biomedical & Life Sciences
ID Code: 66861
Deposited By: ep_importer_pure
Deposited On: 30 Sep 2013 23:07
Refereed?: Yes
Published?: Published
Last Modified: 22 Jun 2019 06:20
URI: https://eprints.lancs.ac.uk/id/eprint/66861

Actions (login required)

View Item View Item