Adaptation of standard spreadsheet software for the analysis of DNA sequences

McEwan, Neil R. and Gatherer, Derek (1998) Adaptation of standard spreadsheet software for the analysis of DNA sequences. Biotechniques, 24 (1). 131-136, 138. ISSN 0736-6205

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This paper presents use of spreadsheet software to derive various statistics on nucleotide and codon distribution and frequency from gene sequence data, including chi 2 test and their derivatives, and proportion of nucleotides in the third position. The basic principles can be easily extended to other more complex functions. In addition, it can be used to translate a nucleic acid sequence into a protein sequence or to produce a codon usage table. This adaptation permits sequence analysis without expensive dedicated software and easy modification of the analysis according to the user's requirements. It is also ideal for introducing biological science students to the programming potential of spreadsheets.

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Journal Article
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?? base sequencecodonmolecular sequence datasequence analysis, dnasoftwaregeneral biochemistry,genetics and molecular biologybiotechnologybiochemistry, genetics and molecular biology(all) ??
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26 Sep 2013 15:39
Last Modified:
16 Jul 2024 09:27