Impoinvil, Daniel E and Ooi, Mong How and Diggle, Peter and Caminade, Cyril and Cardosa, Mary Jane and Morse, Andrew P and Baylis, Matthew and Solomon, Tom (2013) The effect of vaccination coverage and climate on Japanese encephalitis in sarawak, malaysia. PLoS Neglected Tropical Diseases, 7 (8). e2334.
Full text not available from this repository.Abstract
Japanese encephalitis (JE) is the leading cause of viral encephalitis across Asia with approximately 70,000 cases a year and 10,000 to 15,000 deaths. Because JE incidence varies widely over time, partly due to inter-annual climate variability effects on mosquito vector abundance, it becomes more complex to assess the effects of a vaccination programme since more or less climatically favourable years could also contribute to a change in incidence post-vaccination. Therefore, the objective of this study was to quantify vaccination effect on confirmed Japanese encephalitis (JE) cases in Sarawak, Malaysia after controlling for climate variability to better understand temporal dynamics of JE virus transmission and control.