Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) : a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

Crossman, Arthur T. and Urbaniak, Michael D. and Ferguson, Michael A. J. (2008) Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) : a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis. Carbohydrate Research, 343 (9). pp. 1478-1481. ISSN 0008-6215

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Abstract

1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) was prepared to probe the reaction mechanism of the putative zinc-dependent metalloenzyme 2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1-->6)-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis.

Item Type:
Journal Article
Journal or Publication Title:
Carbohydrate Research
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1300/1303
Subjects:
?? enzyme inhibitorsglucosamineglycosylphosphatidylinositolshydroxyureainositol phosphatesmetalloproteinsmolecular structurebiochemistryorganic chemistryanalytical chemistry ??
ID Code:
66394
Deposited By:
Deposited On:
17 Sep 2013 08:08
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 14:12