Mathematical optimization in intensity modulated radiation therapy

Ehrgott, Matthias and Güler, Çiğdem and Hamacher, Horst W. and Shao, Lizhen (2010) Mathematical optimization in intensity modulated radiation therapy. Annals of Operations Research, 175 (1). pp. 309-365. ISSN 0254-5330

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The design of an intensity modulated radiotherapy treatment includes the selection of beam angles (geometry problem), the computation of an intensity map for each selected beam angle (intensity problem), and finding a sequence of configurations of a multileaf collimator to deliver the treatment (realization problem). Until the end of the last century research on radiotherapy treatment design has been published almost exclusively in the medical physics literature. However, since then, the attention of researchers in mathematical optimization has been drawn to the area and important progress has been made. In this paper we survey the use of optimization models, methods, and theories in intensity modulated radiotherapy treatment design.

Item Type:
Journal Article
Journal or Publication Title:
Annals of Operations Research
Uncontrolled Keywords:
?? intensity modulated radiation therapy optimization mathematical modelsmedical physicsgeneral decision sciencesmanagement science and operations researchdecision sciences(all) ??
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Deposited On:
13 May 2013 13:37
Last Modified:
16 Jul 2024 09:22