8,9,10,10a-tetrahydro-6H-tetrazolo[1,5-a]pyrrolo[2,1-c]pyrazines: New heterocyclic frameworks generated by an Ugi-type multicomponent reaction

Franckevicius, Vilius and Longbottom, Deborah A. and Turner, Richard M. and Ley, Steven V. (2006) 8,9,10,10a-tetrahydro-6H-tetrazolo[1,5-a]pyrrolo[2,1-c]pyrazines: New heterocyclic frameworks generated by an Ugi-type multicomponent reaction. SYNTHESIS, 2006 (19). pp. 3215-3223. ISSN 0039-7881

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Abstract

A one-pot, Ugi-type three-component coupling process between an aldehyde, an isocyanide and proline tetrazole is reported, leading to new heterocyclic structures in good to excellent yields.

Item Type:
Journal Article
Journal or Publication Title:
SYNTHESIS
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1600/1605
Subjects:
?? ugi reactionconvertible isocyanidesolution-phase synthesismit isonitrilenbeta-lactamsmulticomponent reactionstetrazoleproline derivatives4-component condensationderivativesheterocycleschemistryfacile synthesisaldehydesalpha-amino-acidsorganic chemistrycat ??
ID Code:
62822
Deposited By:
Deposited On:
18 Mar 2013 09:35
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 13:40