Franckevicius, Vilius and Cuthbertson, James D. and Pickworth, Mark and Pugh, David S. and Taylor, Richard J. K. (2011) Asymmetric Decarboxylative Allylation of Oxindoles. Organic Letters, 13 (16). pp. 4264-4267. ISSN 1523-7060
Full text not available from this repository.Abstract
An asymmetric decarboxylative palladium-catalyzed allylation of alkyl- and aryl-substituted oxindoles has been developed, enabling the installation of an all-carbon quaternary chiral center at the oxindole 3-position in excellent yields and good to excellent enantioselectivity. An intriguing substrate-dependent reversal in stereoselectivity has been observed, whereby the size of the substituent determines the facial selectivity in the allylation step.
Item Type:
Journal Article
Journal or Publication Title:
Organic Letters
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1300/1303
Subjects:
?? stereocenterspalladium-catalyzed allylationquaternary carbon centersworking modelketonesenol carbonates3-allyl-3-aryl oxindolesenantioselective allylic alkylationtsuji allylationc-hbiochemistryorganic chemistryphysical and theoretical chemistry ??
ID Code:
62815
Deposited By:
Deposited On:
15 Mar 2013 11:33
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 13:40