3-Chloromethylpyridyl Bipyridine fac Tricarbonyl Rhenium: A Thiol-Reactive Lumophore for Fluorescence Microscopy Accumulates In Mitochondria

Amoroso, Angelo J. and Arthur, Richard J. and Coogan, Michael and Court, Jonathan B. and Fernandez-Moreira, Vanesa and Hayes, Anthony J. and Lloyd, David and Millet, Coralie and Pope, Simon J. A. (2008) 3-Chloromethylpyridyl Bipyridine fac Tricarbonyl Rhenium: A Thiol-Reactive Lumophore for Fluorescence Microscopy Accumulates In Mitochondria. New Journal of Chemistry, 32 (7). pp. 1097-1102. ISSN 1369-9261

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Abstract

The 3-chloromethylpyridyl bipyridine fac tricarbonyl rhenium cation is a thiol-reactive luminescent agent with a long luminescence lifetime and large Stokes shift that is demonstrated by co-localisation studies to accumulate in mitochondria. This represents the first application of a 3MLCT luminescent agent for the specific targeting of a biological entity in imaging.

Item Type: Journal Article
Journal or Publication Title: New Journal of Chemistry
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/1500/1503
Subjects:
ID Code: 62500
Deposited By: ep_importer_pure
Deposited On: 20 Feb 2013 16:26
Refereed?: Yes
Published?: Published
Last Modified: 25 Feb 2020 07:08
URI: https://eprints.lancs.ac.uk/id/eprint/62500

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