3-Chloromethylpyridyl Bipyridine fac Tricarbonyl Rhenium: A Thiol-Reactive Lumophore for Fluorescence Microscopy Accumulates In Mitochondria

Amoroso, Angelo J. and Arthur, Richard J. and Coogan, Michael and Court, Jonathan B. and Fernandez-Moreira, Vanesa and Hayes, Anthony J. and Lloyd, David and Millet, Coralie and Pope, Simon J. A. (2008) 3-Chloromethylpyridyl Bipyridine fac Tricarbonyl Rhenium: A Thiol-Reactive Lumophore for Fluorescence Microscopy Accumulates In Mitochondria. New Journal of Chemistry, 32 (7). pp. 1097-1102. ISSN 1369-9261

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Abstract

The 3-chloromethylpyridyl bipyridine fac tricarbonyl rhenium cation is a thiol-reactive luminescent agent with a long luminescence lifetime and large Stokes shift that is demonstrated by co-localisation studies to accumulate in mitochondria. This represents the first application of a 3MLCT luminescent agent for the specific targeting of a biological entity in imaging.

Item Type:
Journal Article
Journal or Publication Title:
New Journal of Chemistry
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1500/1503
Subjects:
ID Code:
62500
Deposited By:
Deposited On:
20 Feb 2013 16:26
Refereed?:
Yes
Published?:
Published
Last Modified:
26 May 2020 03:03