Recovery of erythromycin from aqueous solutions with an ionic liquid and high-pressure carbon dioxide

Manic, Marina S. and da Ponte, Manuel Nunes and Najdanovic, Vesna (2011) Recovery of erythromycin from aqueous solutions with an ionic liquid and high-pressure carbon dioxide. Chemical Engineering Journal, 171 (3). pp. 904-911. ISSN 1385-8947

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Abstract

Recovery of erythromycin from aqueous solutions was studied in two steps: (i) single- and multi-stage extraction of erythromycin from an aqueous solution with a hydrophobic ionic liquid, 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide [BMPyrrol][Tf(2)N], as a function of pH and feed to solvent volume ratio, and (ii) high-pressure CO(2) extraction of erythromycin from the ionic liquid, as a function of pressure, temperature and presence of water. Furthermore, data on the mutual solubilities of the hydrophobic ionic liquid and water, as well as on the solubility of erythromycin in [BMPyrrol][Tf(2)N], were obtained. The chemical stability of erythromycin in water-free and water saturated ionic liquid was tested. These results allowed the evaluation of the coupling of liquid-liquid and high-pressure CO(2) extractions. (C) 2011 Elsevier B.V. All rights reserved.

Item Type:
Journal Article
Journal or Publication Title:
Chemical Engineering Journal
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2300/2304
Subjects:
?? organic mixtureswaterseparation2-phase systemsupercritical co(2)antibiotictemperatureenvironmental chemistrygeneral chemical engineeringgeneral chemistryindustrial and manufacturing engineeringchemical engineering(all)chemistry(all) ??
ID Code:
62336
Deposited By:
Deposited On:
13 Feb 2013 14:52
Refereed?:
Yes
Published?:
Published
Last Modified:
16 Jul 2024 09:17