Measurement of [11C]CO2 in exhaled air with a positron-sensitive single-wire proportional counter after i.v. injection of [11C] acetate

Sipila, H.T. and Heselius, S.-J. and Kalliokoski, Matti and Kemppainen, J and Minn, H and Tolvanen, T and Roivainen, A (2011) Measurement of [11C]CO2 in exhaled air with a positron-sensitive single-wire proportional counter after i.v. injection of [11C] acetate. In: 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference. IEEE, Valencia, pp. 2397-2399. ISBN 978-1-4673-0118-3

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Abstract

A positron-sensitive, large window single-wire proportional counter was used for measurements of [11C]CO2 in exhaled air after i.v. injection of [11C] acetate. The performance of the proportional counter was studied using Geant4 and Garfield simulation tools as well as experimentally by injections of known amounts of radioactive gas into measuring volume. The proportional counter was found to be sensitive enough for measuring the low concentrations of [11C]CO2 in the air exhaled by patients after i.v. injection of an 11C-labelled radiopharmaceutical. The limit of detection was 200 Bq/L for [11C]CO2.

Item Type:
Contribution in Book/Report/Proceedings
ID Code:
61495
Deposited By:
Deposited On:
03 Jan 2013 09:07
Refereed?:
Yes
Published?:
Published
Last Modified:
01 May 2020 07:26