Trials in primary care : statistical issues in the design, conduct and evaluation of complex interventions

Lancaster, G A and Campbell, M J and Eldridge, S and Farrin, A and Marchant, M and Muller, S and Perera, R and Peters, T J and Prevost, A T and Rait, G (2010) Trials in primary care : statistical issues in the design, conduct and evaluation of complex interventions. Statistical Methods in Medical Research, 19 (4). pp. 349-377. ISSN 1477-0334

Full text not available from this repository.

Abstract

Trials carried out in primary care typically involve complex interventions that require considerable planning if they are to be implemented successfully. The role of the statistician in promoting both robust study design and appropriate statistical analysis is an important contribution to a multi-disciplinary primary care research group. Issues in the design of complex interventions have been addressed in the Medical Research Council's new guidance document and over the past 7 years by the Royal Statistical Society's Primary Health Care Study Group. With the aim of raising the profile of statistics and building research capability in this area, particularly with respect to methodological issues, the study group meetings have covered a wide range of topics that have been of interest to statisticians and non-statisticians alike. The aim of this article is to provide an overview of the statistical issues that have arisen over the years related to the design and evaluation of trials in primary care, to provide useful examples and references for further study and ultimately to promote good practice in the conduct of complex interventions carried out in primary care and other health care settings. Throughout we have given particular emphasis to statistical issues related to the design of cluster randomised trials.

Item Type:
Journal Article
Journal or Publication Title:
Statistical Methods in Medical Research
Uncontrolled Keywords:
/dk/atira/pure/core/keywords/mathsandstatistics
Subjects:
?? mathematics and statisticshealth information managementepidemiologystatistics and probabilityqa mathematics ??
ID Code:
55096
Deposited By:
Deposited On:
14 Jun 2012 07:51
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 12:54