Liu, Zhengtao and Wang, Hong and Carmichael, Paul L. and Deag, Eliot J. and Duarte-Davidson, Raquel and Li, Hong and Howe, Paul and Meng, Wei and Price, Oliver R. and Shen, Yingwa and Shore, Richard F. and Sweetman, Andrew J. and Yan, Zhen-guang and Zang, Wen chao and Undemann, Emma and Jones, Kevin C. (2012) China begins to position for leadership on responsible risk-based global chemicals management. Environmental Pollution, 165. pp. 170-173. ISSN 0269-7491
Full text not available from this repository.Abstract
Section 5 of the Toxic Substances Control Act (TSCA) does not require any toxicity testing as a prerequisite for submission of a Premanufacturing Notice (PMN) for a new chemical. In order to compensate for the lack of actual test data, a process involving structure-activity relationships (SAR) for assessing hazard potential was constructed. The hazard assessment is then coupled with an estimation of potential exposure to determine potential risk. This process involves the use of multiple interdisciplinary teams that work within a 90-day time frame to complete approximately 2000 risk assessments per year.