New self-adaptive probabilistic neural networks in bioinformatic and medical tasks

Georgiou, Vassilis L. and Pavlidis, Nicos and Parsopoulos, Kostantinos E. and Alevizos, Philipos D. and Vrahatis, Michael N. (2006) New self-adaptive probabilistic neural networks in bioinformatic and medical tasks. International Journal on Artificial Intelligence Tools, 15 (3). pp. 371-396. ISSN 0218-2130

Abstract

We propose a self–adaptive probabilistic neural network model, which incorporates optimization algorithms to determine its spread parameters. The performance of the proposed model is investigated on two protein localization problems, as well as on two medical diagnostic tasks. Experimental results are compared with that of feedforward neural networks and support vector machines. Different sampling techniques are used and statistical tests are conducted to calculate the statistical significance of the results.