Ion channels as electrostatic amplifiers of charge fluctuations

Luchinsky, D. G. and Tindjong, R. and Kaufman, I. and McClintock, P. V. E. and Eisenberg, R. S. (2008) Ion channels as electrostatic amplifiers of charge fluctuations. Journal of Physics: Conference Series, 142 (1): 012049. ISSN 1742-6588

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Electrostatic interactions between ions in an ionic channel and the charge fluctuations in the channel mouth are considered. It is shown that the charge fluctuations can be enhanced in channels of low dielectric constant, resulting in strong modulation of the potential barrier at the selectivity site. It is conjectured that similar effects can alter transition probabilities in other molecular dynamical systems.

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Journal Article
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Journal of Physics: Conference Series
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“Published under licence in Journal of Physics: Conference Series by IOP Publishing Ltd. Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.”
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Deposited On:
07 Jan 2010 12:13
Last Modified:
09 Apr 2024 23:38