Hardy, John (2024) Stimuli-responsive biomaterials for medical and technical applications. In: Emerging Technologies Community Conference 2024, 2024-07-16 - 2024-07-18, Shrivenham Defence Academy.
Full text not available from this repository.Abstract
Here, we report the development of stimuli-responsive polymers (demonstrated to be cytocompatibility via a combination of in silico/in vitro/in vivo studies) and their application for medical applications, including electroactive/photoactive polymers for delivery of clinically relevant drugs, and electroactive polymers for stimulation of cells, for various tissue paradigms (including ocular, otology, rhinology, nerve & skin). Moreover, we present proof of concept that multi-stimulus responsive materials can be used to reconfigure themselves in response to triggers from externally applied stimuli which is potentially useful for architecture, orthotics and prosthetics. Contributors: Hend Abdelmohsen & Leah Pomfret (PhD students). Collaborators at Lancaster University: Adam Blaney (Architecture & Design), Richard Mort (Biomedical and Life Sciences), David Cheneler (Engineering). Collaborators at Keele University: Chris Adams (Neuroscience). Collaborators at NHS: Pierre Martin-Hirsch & others. Biomaterials capable of responding to stimuli present a variety of opportunities for medical and technical applications. We present an overview of our recent progress in materials science & engineering (e.g., adaptable architecture, orthotics & prosthetics); drug delivery (ocular, otology, rhinology, skin & other); and tissue engineering (nerve & skin).