P Matrix Properties, Injectivity, and Stability in Chemical Reaction Systems

Banaji, Murad and Donnell, Pete and Baigent, Stephen (2007) P Matrix Properties, Injectivity, and Stability in Chemical Reaction Systems. SIAM Journal on Applied Mathematics, 67 (6). pp. 1523-1547.

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Abstract

In this paper we examine matrices which arise naturally as Jacobians in chemical dynamics. We are particularly interested in when these Jacobians are P matrices (up to a sign change), ensuring certain bounds on their eigenvalues, precluding certain behavior such as multiple equilibria, and sometimes implying stability. We first explore reaction systems and derive results which provide a deep connection between system structure and the P matrix property. We then examine a class of systems consisting of reactions coupled to an external rate-dependent negative feedback process and characterize conditions which ensure that the P matrix property survives the negative feedback. The techniques presented are applied to examples published in the mathematical and biological literature.

Item Type:
Journal Article
Journal or Publication Title:
SIAM Journal on Applied Mathematics
ID Code:
231022
Deposited By:
Deposited On:
29 Jul 2025 10:50
Refereed?:
Yes
Published?:
Published
Last Modified:
29 Jul 2025 10:50