Research progress on peptides that inhibit melanin synthesis

Yu, Binrui and Wang, Nailong and Cai, Shanshan and Yan, Hao and Sun, Shaojia and Wang, Siru and Li, Ye and Liang, Zhengting (2025) Research progress on peptides that inhibit melanin synthesis. Frontiers in Pharmacology, 16: 1610623. ISSN 1663-9812

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Abstract

Melanin produced by melanocytes, primarily determines human skin color and protects against ultraviolet radiation. However, excessive melanin deposition can lead to skin conditions such as freckles, age spots, and moles, potentially causing aesthetic concerns and psychological distress. Consequently, there is significant research interest in developing safe and effective whitening products that inhibit melanin synthesis. Bioactive peptides represent a promising compound category that effectively reduces melanin synthesis with minimal side effects. This review explores melanin pigmentation, identifies sources of peptides that inhibit melanin synthesis, and elucidates the mechanisms by which these peptides operate, aiming to contribute to developing novel whitening products.

Item Type:
Journal Article
Journal or Publication Title:
Frontiers in Pharmacology
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2700/2736
Subjects:
?? bioactive peptidesexcessive depositioninhibitiontyrosinasewhiteningmelaninpharmacology (medical)pharmacology ??
ID Code:
230829
Deposited By:
Deposited On:
31 Jul 2025 12:25
Refereed?:
Yes
Published?:
Published
Last Modified:
31 Jul 2025 12:25