Community acceptance of a novel malaria intervention, Attractive Targeted Sugar Baits, in the Zambia phase III trial

Orange, Erica and Arnzen, Annie and Muluma, Chuma and Akalalambili, Situmbeko and Tobolo, Titus and Ndalama, Frank and Chishya, Chama and Saili, Kochelani and Ashton, Ruth A. and Eisele, Thomas P. and Yukich, Joshua and Kyomuhangi, Irene and Miller, John and Silumbe, Kafula and Chanda, Javan and Hamainza, Busiku and Wagman, Joseph and Slutsker, Laurence and Burkot, Thomas R. and Littrell, Megan (2024) Community acceptance of a novel malaria intervention, Attractive Targeted Sugar Baits, in the Zambia phase III trial. Malaria Journal, 23 (1): 240. ISSN 1475-2875

Abstract

Background: Community acceptance is an important criterion to assess in community trials, particularly for new tools that require high coverage and use by a target population. Installed on exterior walls of household structures, the attractive targeted sugar bait (ATSB) is a new vector control tool designed to attract and kill mosquitoes. ATSBs were evaluated in Western Zambia during a two-year cluster randomized controlled trial to assess the efficacy of ATSBs in reducing malaria transmission. Community acceptance of ATSBs was critical for successful trial implementation. Methods: A community engagement strategy outlined activities and key messages to promote acceptance. Annual cross-sectional surveys, conducted during the peak transmission period, assessed households for presence of ATSBs as well as perceived benefits, concerns, and willingness to use ATSBs. Sixteen focus group discussions and 16 in-depth interviews, conducted at the end of each ATSB station deployment period, obtained a range of perceptions and household experiences with ATSB stations, as well as ITN use in the context of ATSB deployment. Results: Methods used during the study to promote acceptance and continued use of ATSBs were effective in achieving greater than 90% coverage, a high (greater than 70%) level of perceived benefits, and fewer than 10% of households reporting safety concerns. Common facilitators of acceptance included the desire for protection against malaria and reduction of mosquitoes, trust in health initiatives, and understanding of the product. Common barriers to acceptance included misconceptions of product impact on mosquitoes, continued cases of malaria, association with satanism, and damage to household structures. Discussion: Future use of the ATSB intervention will likely require activities that foster community acceptance before, during, and after the intervention is introduced. Additional research may be needed to understand the impact of different levels of community engagement on ATSB station coverage, ATSB station perception, and ITN use. Conclusion: There was high acceptance of ATSB stations during the trial in Western Zambia. Continuous and intense community engagement efforts contributed to sustained ATSB coverage and trust in the product. Acceptance of ATSBs during programmatic delivery requires further research.