Innate immune sensing by cGAS-STING in animals reveals unexpected messengers

Unterholzner, L. (2023) Innate immune sensing by cGAS-STING in animals reveals unexpected messengers. Cell, 186 (15). pp. 3145-3147. ISSN 0092-8674

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Abstract

The DNA sensor cGAS and its adaptor STING constitute an ancient pathogen detection mechanism, but it is unclear to what extent its function is conserved across the animal kingdom. In this issue of Cell, Kranzusch and colleagues identify thousands of cGAS-like receptors and discover networks of second messengers that activate innate immune responses in animals.

Item Type:
Journal Article
Journal or Publication Title:
Cell
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1300/1300
Subjects:
?? general biochemistry,genetics and molecular biologybiochemistry, genetics and molecular biology(all) ??
ID Code:
221352
Deposited By:
Deposited On:
14 Jun 2024 11:20
Refereed?:
Yes
Published?:
Published
Last Modified:
16 Jul 2024 12:04