Coupled bullet physics and computational fluid dynamics as a tool for modeling the freeze-drying of microparticles

Capozzi, Luigi and Boccardo, Gianluca and Barresi, Antonello A. and Pisano, Roberto (2015) Coupled bullet physics and computational fluid dynamics as a tool for modeling the freeze-drying of microparticles. Szent István University, Gödöllő, Hungary.

Abstract

A multi-scale modelling approach is proposed to better understand the behaviour of the freeze-drying of packed-bed of uniform and non-uniform particles. In particular, realistic geometric packing arrangements have been generated by using a bullet physics engine, while CFD simulation at the pore-scale has been used in order to obtain realistic values for the packed-bed; the results have then been used in a two-dimensional model describing heat and mass transfer in the freeze-drying of the packed-bed made of frozen particles.