Neuropeptides in the rat claustrum - An immunohistochemical detection

Lipiec-Borowicz, Anna and Pałasz, Artur and Suszka-Świtek, Aleksandra and Filipczyk, Łukasz and Della Vecchia, Alessandra and Worthington, John J and Piwowarczyk-Nowak, Aneta (2024) Neuropeptides in the rat claustrum - An immunohistochemical detection. Acta histochemica, 126 (3): 152156. ISSN 1618-0372

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Abstract

Neuropeptides are involved in numerous brain activities and are responsible for a wide spectrum of higher mental functions. The main purpose of this outline structural qualitative study was to identify the possible immunoreactivity of classical neuropeptides, as well as novel ones such as nesfatin-1, phoenixin (PNX), spexin (SPX), neuromedin U (NMU) and respective receptors within the rat claustrum for the first time. The study shows the novel identification of peptidergic neurotransmission in the rat claustrum which potentially implicates a contribution of this neuropeptide to numerous central neurosecretory mechanisms.