Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process

Ross, Mark and Lithgow, Hannah Margaret and Hayes, Lawrence D and Florida-James, Geraint (2019) Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process. In: Biochemistry and Cell Biology of Ageing :. UNSPECIFIED, pp. 311-338. ISBN 9789811336812

Abstract

Exercise in young adults has been consistently shown to improve various aspects of physiological and psychological health but we are now realising the potential benefits of exercise with advancing age. Specifically, exercise improves cardiovascular, musculoskeletal, and metabolic health through reductions in oxidative stress, chronic low-grade inflammation and modulating cellular processes within a variety of tissues. In this this chapter we will discuss the effects of acute and chronic exercise on these processes and conditions in an ageing population, and how physical activity affects our vasculature, skeletal muscle function, our immune system, and cardiometabolic risk in older adults.