Economic analysis of a freeze-drying cycle

Stratta, Lorenzo and Capozzi, Luigi C. and Franzino, Simone and Pisano, Roberto (2020) Economic analysis of a freeze-drying cycle. Processes, 8 (11): 1399. pp. 1-17. ISSN 2227-9717

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Abstract

Freeze-drying has always been considered an extremely expensive procedure to dehydrate food or pharmaceutical products, and for this reason, it has been employed only if strictly necessary or when the high added value of the final product could justify the costs. However, little effort has been made to analyze the factors that make this technology so unaffordable. In this work, a model was proposed to calculate in detail the operational (OC) and capital costs (CC) of a freeze-drying cycle and an evaluation of the process bottlenecks was made. The main result is that the process itself, contrary to the classic belief, is not the most expensive part of freeze-drying, while the initial investment is the real limiting factor. Under this consideration, the optimization of a freeze-drying cycle should be formulated in order to fit more cycles in the lifespan of the apparatus, instead of merely reducing the power consumption of the machine.

Item Type:
Journal Article
Journal or Publication Title:
Processes
Additional Information:
Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1500/1502
Subjects:
?? costs analysisfreeze-dryinglyophilizationoptimizationbioengineeringchemical engineering (miscellaneous)process chemistry and technology ??
ID Code:
215215
Deposited By:
Deposited On:
26 Feb 2024 09:40
Refereed?:
Yes
Published?:
Published
Last Modified:
26 Feb 2024 09:40