Li, G. and Shen, E. and Liang, L. and Li, K. and Lu, Y. and Zhu, W. and Tian, Y. and Baker, I. and Wu, H. (2022) Microstructure and corrosion resistance of powder metallurgical Ti-Nb-Zr-Mg alloys with low modulus for biomedical application. Materials Characterization, 192: 112223. ISSN 1044-5803
Full text not available from this repository.Abstract
Due to their bioinert nature, titanium alloys show poor bone-implant integration and insufficient osseointegration in vivo. In this study, a series of low elastic modulus bioactive titanium alloys with a nominal composition of Ti-13Nb-13Zr-1.25 Mg (wt%) were prepared using mechanical alloying and spark plasma sintering techniques. The microstructures, mechanical properties, degradation behaviors and in vitro bioactivities of these alloys were systematically investigated. After sintering at 700 °C, the α-Ti, β-Ti and Nb (Zr)-rich phases were present, and the Mg was uniformly distributed. In addition to above-mentioned phases, the α″ phase was found after sintering at 800 °C or 900 °C. The density, elastic modulus, yield strength, ultimate compressive strength and corrosion resistance all increased with increasing sintering temperature. After sintering at 900 °C, the alloy exhibited high density (99.8%), good compressive strength (1417.2 MPa) and excellent corrosion resistance. In addition, it had a lower elastic modulus (~69 GPa) than that of the biomedical alloy Ti–13Nb–13Zr (~80 GPa). In vitro experiments showed that the alloys sintered at either 800 °C or 900 °C promoted cell adhesion and proliferation. However, the alloy sintered at 700 °C inhibited cell proliferation, which was due to the greater release of Mg 2+. Thus, the optimally-processed Ti-Nb-Zr-Mg alloy sintered at 900 °C shows immense potential as a biomedical material.