Okoyo, Collins and Minnery, Mark and Orowe, Idah and Owaga, Chrispin and Campbell, Suzy J. and Wambugu, Christin and Olick, Nereah and Hagemann, Jane and Omondi, Wyckliff P. and McCracken, Kate and Montresor, Antonio and Medley, Graham F. and Fronterre, Claudio and Diggle, Peter and Mwandawiro, Charles (2023) Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya:Results from ten-years of the Kenya national school-based deworming programme. Heliyon, 9 (10). ISSN 2405-8440
Full text not available from this repository.Abstract
Background Kenya is endemic for soil-transmitted helminths (STH) with over 6 million children in 27 counties currently at-risk. A national school-based deworming programme (NSBDP) was launched in 2012 with a goal to eliminate parasitic worms as a public health problem. This study used model-based geostatistical (MBG) approach to design and analyse the impact of the NSBDP and inform treatment strategy changes. Methods A cross-sectional study was used to survey 200 schools across 27 counties in Kenya. The study design, school selection and analysis followed the MBG approach which incorporated historical data on treatment, morbidity and environmental covariates to efficiently predict the helminths prevalence in Kenya. Results Overall, the NSBDP geographic area prevalence for any STH was estimated to sit between 2 % and 0.999. Species-specific thresholds were between 2 % and 0.999. Conclusions Based on the World Health Organization guidelines, STH treatment requirements can now be confidently refined. Ten counties may consider suspending treatment and implement appropriate surveillance system, while another 10 will require treatment once every two years, and the remaining seven will require treatment once every year.