Manganese-Based Carbon Monoxide-Releasing Molecules: A Multitude of Organometallic Pharmaceutical Candidates Primed for Further Biological Analysis

Ward, Jonathan (2021) Manganese-Based Carbon Monoxide-Releasing Molecules: A Multitude of Organometallic Pharmaceutical Candidates Primed for Further Biological Analysis. In: Comprehensive Organometallic Chemistry IV. Elsevier. ISBN 9780124095472

Abstract

An overview of manganese-based drugs with a focus on CO-releasing molecules is presented. Synthesis, characterization and biological activity from important literature are summarized. A range of topics are discussed including: Modes of CO-release, emerging design rules to obtain particular modes of CO-release, and developing CO-releasing molecules (CO-RMs) to release CO with low energy visible light.