Roberts, Dean and McLaughlin, Mark (2023) Platinum Catalysed Hydrostannylation of Terminal Alkynes:Highly Selective Synthesis of Vinyl Stannanes. Advanced Synthesis & Catalysis, 365 (10). pp. 1602-1606. ISSN 1615-4150
Full text not available from this repository.Abstract
We present the first study on the application of platinum complexes in the hydrostannylation of terminal alkynes. A range of platinum complexes were screened, with PtCl 2/XPhos proving to provide the best selectivity for the β-(E)-vinyl stannane. The catalyst system is able to provide the corresponding vinyl stannane in selectivities which surpasses that which is typically afforded under palladium catalysis. Additionally, a telescoped hydrometallation/cross-coupling sequence has been developed, allowing for application of the vinyl stannanes without excessive manipulation or purification of the intermediate stannane. (Figure presented.).