Evaluation of an electrochemical sensor for measuring blood ketones.

Bryne, H. A. and Tieszen, K. L. and Hollis, S. and Dornan, T. L. (2000) Evaluation of an electrochemical sensor for measuring blood ketones. Diabetes Care, 23 (4). pp. 500-503. ISSN 1935-5548

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OBJECTIVE: To evaluate the performance of a hand-held ketone sensor that is able to measure blood beta-hydroxybutyrate (beta-HBA) concentrations within 30 s in patients with diabetic ketoacidosis (DKA) and patients who attend a weight management clinic. RESEARCH DESIGN AND METHODS: Two groups of patients were studied: 19 patients admitted with DKA and 156 patients attending a weight management clinic. Paired capillary and venous whole blood samples were measured using the ketone sensor and also using an enzymatic laboratory reference method. RESULTS: The ketone sensor accurately measured beta-HBA concentrations in patients with DKA (limits of agreement -0.9 to + 1.0 mmol/l) or starvation-induced ketonemia (limits of agreement -0.5 to +0.5 mmol/l). CONCLUSIONS: This ketone sensor accurately measures whole blood beta-HBA concentrations within 30 s.

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Journal Article
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Diabetes Care
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21 Nov 2008 12:03
Last Modified:
09 Mar 2022 08:07