Prospective donors’ perspectives on hematopoietic cell donation for cell and gene therapy research and development

Hamad, Lina and Anthias, Chloe and O'Leary, Ann and Gibson, Daniel and Machin, Laura (2023) Prospective donors’ perspectives on hematopoietic cell donation for cell and gene therapy research and development. Regenerative Medicine, 18 (4). pp. 301-311.

Text (RME-2022-0195_Proof_hi)
RME_2022_0195_Proof_hi.pdf - Accepted Version
Available under License Creative Commons Attribution-NonCommercial.
Download (821kB)

Abstract

Aims: To explore prospective donors’ attitudes and perceptions towards donating hematopoietic stem cells (HSCs) for novel treatments research and development (R&D). Methods: A survey was launched by Anthony Nolan (AN) to assess prospective donors’ willingness to donate HSCs for novel therapies R&D, and their degree of comfort with the AN collaborating with and receiving payment from external organizations. Results: Most participants (87%) were willing to donate for novel treatment R&D and were comfortable with AN collaborating with external organizations and receiving payment (91% and 80%, respectively). Conclusion: Results reveal an overall positive response towards donating HSCs for R&D. These findings can support stakeholders and policymakers in outlining donation practices that uphold donors’ safety and welfare.