Physics of cellular energy metabolism

Barnes, S.J.K. and Stefanovska, A. (2022) Physics of cellular energy metabolism. Contemporary Physics, 62 (3). pp. 125-143. ISSN 0010-7514

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Abstract

Contributions to the field of cellular energy metabolism have been dominated by biochemistry. Over the past decade, however, several physics-based approaches have been introduced. Oscillations are an intrinsic aspect of all living systems, from fluctuating substrate levels within cells to changes in electrical potential across membranes. Utilising physics-based approaches to analyse these time-dependent signals reveals pockets of predictable stability. By embracing the nonlinear, time-varying and open nature of cellular dynamics, new network-based approaches to modelling cells are emerging, capable of effectively replicating measured time-series data. These new approaches promise to bring greater comprehension of how various illnesses affect the cells, and indeed, to novel treatments or diagnostic methods.

Item Type:
Journal Article
Journal or Publication Title:
Contemporary Physics
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/3100
Subjects:
ID Code:
183998
Deposited By:
Deposited On:
13 Jan 2023 15:00
Refereed?:
Yes
Published?:
Published
Last Modified:
13 Jan 2023 15:00